![]() So, are soil-based probiotics unsafe, or are they safe and helpful? Others claim these species may cause a severe immune response in patients with a compromised immune system. Some claim spore-based probiotics may become invasive in the human gut. In some circles, soil-based probiotics have a reputation for doing harm. Another study showed that Bacillus subtilis R0179 populated the digestive tract but didn’t improve gut symptoms. In two studies, children with acute diarrhea showed no meaningful benefit with illness duration, stool consistency, or stool frequency from soil-based probiotics .
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